翻訳と辞書 Words near each other ・ Factoryville, Pennsylvania ・ Factoría de Ficción ・ Factoría de Ficción (pay television) ・ Factor analysis of information risk ・ Factor analysis of mixed data ・ Factor base ・ Factor cost ・ Factor D ・ Factor endowment ・ Factor graph ・ Factor H ・ Factor I ・ Factor I Deficiency ・ Factor I deficiency ・ Factor income ・ Factor IX ・ Factor market ・ Factor of automorphy ・ Factor of safety ・ Factor oracle ・ Factor payments ・ Factor price ・ Factor price equalization ・ Factor Prize for Southern Art ・ Factor regression model ・ Factor shares ・ Factor system ・ Factor T ・ Factor theorem ・ Factor Three Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Factor IX ： ウィキペディア英語版 Factor IX Factor IX (or Christmas factor) () is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B. It was discovered in 1952 after a young boy named Stephen Christmas was found to be lacking this exact factor, leading to hemophilia. == Physiology == Factor IX is produced as a zymogen, an inactive precursor. It is processed to remove the signal peptide, glycosylated and then cleaved by factor XIa (of the contact pathway) or factor VIIa (of the tissue factor pathway) to produce a two-chain form where the chains are linked by a disulfide bridge. When activated into factor IXa, in the presence of Ca2+, membrane phospholipids, and a Factor VIII cofactor, it hydrolyses one arginine-isoleucine bond in factor X to form factor Xa. Factor IX is inhibited by antithrombin.〔 Factor IX expression increases with age in humans and mice. In mouse models mutations within the promoter region of factor IX have an age-dependent phenotype. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Factor IX」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.